Cultures were observed for atleast one year. Results: From macroscopically affected colon, MAP-DNA was detected in 48.6%, 39% and 35.9% patients with CD, UC and controls, respectively (p = .001). MAP culture was positive in 14.3%, 11.4%, 14.3% (p = .08)patients with CD, UC and ITB,

respectively. From buffy coat MAP-DNA was detected in 16.1%, 19.5%, 25.7% and 14.7% (p = .66)patients and a positive MAP culture in 16.1%, 9.7%, 8.8% and 3% with CD, UC, ITB and controls, respectively. There was no correlation between MAP-PCR or MAP-culture positivity and disease location, disease duration http://www.selleckchem.com/products/mitomycin-c.html or use of immunosuppressive drugs. Conclusion: While MAP-DNA is detected in a slightly higher number of patients with CD, MAP could be cultured in equal proportion of patients with CD, UC and even ITB. These observations while do not overtly support an association between MAP and CD; an inhibitory role of mesalamines and azathioprine on MAP viability might be

playing a role in a low culture positivity. Key Word(s): 1. MAP; 2. Crohn’s disease; 3. ITB; 4. ulcerative colitis; Presenting Author: ROBERTA PICA Additional Authors: CLAUDIO CASSIERI, ELEONORAVERONICA AVALLLONE, MADDALENA ZIPPI, PIETRO CRISPINO, FRANCESCA MACCIONI, PAOLO PAOLUZI Corresponding Author: ROBERTA PICA Affiliations: IG-IBD Objective: Wireless capsule endoscopy (WCE) and Magnetic resonance enteroclysis (MRE) are techniques used for the evaluation of small bowel lesions, especially for Crohn’s disease (CD). Aim was to evaluate the efficacy BIBW2992 clinical trial and safety of WCE in comparison to MRE in patients with diagnosed or suspected CD. Methods: Sixteen consecutive patients (8 M, 8 F, median age: 46.2 years, range: 18–75) (14 with established diagnosis of CD and 2 suspected) were studied. All underwent a preliminary study with small bowel follow through (SBFT). In case of significant bowel stricture (<12 mm) WCE was not performed. Results: None

of the patients was receiving non-steroidal anti- inflammatory drugs. MRE was performed in all patients except 1 (claustrophobic reaction) and detected inflammatory lesions (reduction bowel lumen, disruption of the fold pattern or increased contrast uptake) in 11 cases (15/16, 73%). WCE was performed in 10 patients (5 were excluded for significant bowel strictures and 1 was unable to swallow the capsule.) see more and detected significant lesions (erythema, aphtas, ulcers, fissures or mucosal hemorrhages) in 9 cases (90%). Nine patients have been evaluated with both examinations: WCE detected inflammatory lesions of the small bowel in 8 cases (90%), while MRE in 6 cases (67%). Among the 3 patients negative for lesions of the small bowel at MRE, 1 resulted negative also at WCE, while the other 2 showed significant lesions of terminal ileum at WCE. Conclusion: WCE and MRE appear in the present study as complementary methods for diagnosing small bowel CD. Key Word(s): 1. CROHN’S DISEASE; 2. WCE; 3.