00 PM 143: The risk for hepatocellular carcinoma among patients w

00 PM 143: The risk for hepatocellular carcinoma among patients with chronic HCV infection and advanced hepatic fibrosis following sustained virological response Adriaan J. van der Meer, Jordan J. Feld, Harald Hofer, Piero L. Almasio, Vincenza Calvaruso, Conrado M. Fernandez-Rodriguez, Soo Aleman, Nathalie Ganne-Carrie, Roberta D’Ambrosio, Stanislas

Pol, Maria Trapero-Marugan, Ricardo Moreno-Otero, Vincent Mallet, Rolf W. Hultcrantz, Ola Weiland, Karoline Rutter, Vito Di Marco, Sonia Alonso, Savino Bruno, Massimo Colombo, Robert J. de Knegt, Bart J. Veldt, Bettina E. Hansen, Harry L. Janssen 4:15 PM 144: Sexual function is impaired in men and women with chronic hepatitis C Julien Vergniol, Genevieve

Hou, Juliette Foucher, Florence Chenus, Faberes Carole, Faiza Chermak, Aude Lafourniere, Noui Souakri, Victor de Ledinghen R428 Parallel 21: Inflammation and Fibrosis Monday, November 4 3:00 – 4:30 PM Room 150A MODERATORS: Natalie Torok, MD Robert Schwabe, MD 3:00 PM 145: HIV-infection of Kupffer cells results in a dysregulated response to LPS despite effective AntiRetroviral Therapy Arevik Mosoian, Feng find more Hong, Yedidya Saiman, Adeeb Rahman, Andrea D. Branch, Sasan Roayaie, Sander Florman, Francesc Cunyat, Mario Stevenson, Meena Bansal 3:15 PM 146: HCV is taken up by Flavopiridol (Alvocidib) human liver sinusoidal endothelial cells (LSECs) and triggers IFN Type I and III (lambda) production and autocrine/paracrine signaling that inhibits HCV replication Silvia Giugliano, Lucy Golden-Mason, Evgenia Dobrinskikh, Amy E. Stone, Alejandro Soto-Gutierrez, Michael Gale, Vijay Shah, Hugo R. Rosen 3:30 PM 147: Hepatic sdf-1 (CXCL12)

acts downstream of VEGF to recruit liver sinusoidal endothelial cell progenitor cells from the bone marrow in liver regeneration Laurie D. Deleve, Xiandong Wang, Lei Wang, William A. Gaarde 3:45 PM 148: Hepatic Stellate Cells Orchestrate Clearance of Dead Hepatocytes from the Liver after Acute Injury in a Hypoxia-inducible Factor-1α-dependent Manner Bryan Copple, Aaron Pace, Akie J. Mochizuki, Keara Towery, James P. Luyendyk 4:00 PM 149: Macrophage autophagy protects from liver fibrosis Jasper Lodder, Marie-Noële Chobert, Sophie Lotersztajn, Fatima Teixeira-Clerc 4:15 PM 150: The liver-derived plasma protein histidine-rich glycoprotein promotes chronic liver injury and fibrosis by polarizing hepatic macrophages towards the inflammatory M1 phenotype Matthias Bartneck, Viktor Fech, Josef Ehling, Xiao Wei, Klaudia Warzecha, Kanishka Hittatiya, Nikolaus Gassler, Twan Lammers, Willi Jahnen-Dechent, Christian Trautwein, Frank Tacke Parallel 22: Signaling in Hepatotoxicity Monday, November 4 3:00 – 4:30 PM Room 152A MODERATORS: Craig J. McClain, MD Urs A.

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