1997]. At the same time, compulsive buying, with the advantage of euphoria, can
be considered as a coping strategy during the depression or other negative emotions [Faber and Christenson, 1996; Dittmar and Drury, 2000]. We have contributed to the biological and psychological literature in the field of psychiatry for many years and, ultimately, this has lead us to the formation of the concept of ‘biopsychosocial’. In the etiology Inhibitors,research,lifescience,medical of psychiatric disorders, biological (in this case, the possible immunological effects of drugs), psychological (in this case, the effect of trauma on emotions, thoughts and behaviors), or biopsychosocial (in this case, the effect of possible structural or immunologic changes caused by psychological trauma on emotions, thoughts and behaviors) Inhibitors,research,lifescience,medical explanations are important in determining the correct treatment approaches. Although it was a constraint that the necessary immunological research could not be made in this case, we think that the compulsive buying that occurred in this patient, who has a familial predisposition to OCD, was triggered by the usage of ribavirin or a psychological stressor. Therefore, whether the effects of ribavirin or psychological Inhibitors,research,lifescience,medical stressor on the immune system caused disruption in corticostriatal activity and/or created the ground for OCSD is worthy of controlled clinical
and immunological studies. Footnotes Funding: This research received no specific grant from any funding agency in the public, commercial, or not-for-profit sectors. Contributor Information Görkem Inhibitors,research,lifescience,medical Karakaş Uğurlu, Ministry of www.selleckchem.com/products/cobimetinib-gdc-0973-rg7420.html health Ankara Atatürk Training and Research Hospital, Bilkent road, Number: 3 Bilkent / Ankara 06800, Turkey. Mustafa Uğurlu, Department of Psychiatry, Ministry of Health Ankara Atatürk Training and Research Hospital, Republic of Turkey. Ali Çayköylü, Department of Psychiatry, Yıldırım Beyazıt University Ankara Atatürk Training and Research
Hospital, Republic of Turkey.
In England the adult psychiatric morbidity survey of 2007 found Inhibitors,research,lifescience,medical the weekly community prevalence of a depressive episode to be 2.3% and that for generalized anxiety disorder (GAD) 4.4% [Bebbington et al. 2009]. It is therefore not surprising that depression and anxiety are two of the most common disorders managed by general practitioners (GPs). The vast majority of depression is treated solely in primary care with only about why one in four or five patients with depression referred to secondary mental health services [NICE, 2010]. In the adult psychiatric morbidity survey 24% and 13% of people with depression and GAD respectively had spoken with their GP in the last 2 weeks and 65% and 52% within the last year. This results in a considerable burden on GPs with a UK primary care survey finding that 7.2% of consecutive consultations were for probable depression [Ostler et al. 2001].