Bacteriophages, extremely ubiquitous entities, are in permanent contact with human organisms. They are present in water, food, and soil and constitute a part of the “”microbial flora”" of human skin and gastrointestinal tract and penetrate all tissues. Knowledge about their influence on the human body may be very useful, similar to the knowledge about the
“”beneficial”" strains of bacteria that make up our microflora. There may Metabolism inhibitor also be some “”beneficial”" bacteriophages in our bodies and in our environment. Conclusion The migration of human and mouse melanoma can be inhibited by purified T4 and HAP1 bacteriophage preparations. A response of melanoma cells to LPS (within the investigated range) was not observed, so the antimigration activity of the studied preparations cannot be attributed to LPS. No differences in the effects of T4 and HAP1 on melanoma migration were observed. selleck click here Acknowledgements This work was supported
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