Between the group of 1 week and 3 weeks, a more obvious rising
tendency of both mu CT parameters and the F(max) of implants was observed. After 3 weeks, the tendency of increase tapered off.
Conclusion. The results indicated that early loading may decrease osseointegration of mini-implants. (Oral Surg Oral Med Oral Pathol Oral Radiol Endod 2009; 108: 196-202)”
“Pulmonary alveolar proteinosis (PAP) is a rare lung condition characterised by the accumulation of lipoproteinaceous surfactant material within alveolar airspaces resulting in clinical manifestations ranging from asymptomatic to severe respiratory failure. Three disease subtypes are recognised: autoimmune, secondary and congenital.
We describe two presentations of PAP in the West of Ireland YH25448 in vitro with a review of the current literature.
Autoimmune PAP, associated with the presence of granulocyte-macrophage colony-stimulating factor (GM-CSF) autoantibodies, accounts for
> 90 % of cases. Treatment with whole lung lavage is the current standard of care. Novel therapies Brigatinib targeting alveolar macrophages (recombinant GM-CSF therapy) and anti-GM-CSF antibodies (rituximab, plasmapharesis) are under investigation.
This is a summary of available literature outlining current clinical practice in the diagnosis, management, and treatment of PAP. PAP should be considered in the differential diagnosis of any patient with a restrictive pulmonary defect. Without high clinical suspicion, this diagnosis can easily be missed.”
“Question under study: Over the last decade selleckchem the Swiss health care system has undergone several changes, resulting in stronger economic constraints, heavier administrative workload and limited work autonomy for doctors. In this context we examined the change in burnout prevalence over time among Swiss doctors surveyed during this period.
Methods: Cross-sectional survey data collected by mail in 2002, 2004 and 2007 throughout the country were used. Measures included the Maslach Burnout Inventory (MBI), several socio-demographics (gender, living alone, having children), and work-related characteristics (number of years in current workplace,
hours worked). Answers to the MBI were used to classify respondents into moderate (high score on either the emotional exhaustion or the depersonalisation/cynicism subscales) and high degree of burnout (scores in the range of burnout in all three subscales).
Results: Rates of moderate degree burnout increased from 33% to 42% among general practitioners (p = 0.002) and from 19% to 34% among paediatricians (p = 0.001) (high degree of burnout: 4% to 6% [p = 0.17] and 2% to 4% [p = 0.42] respectively). After adjustment for significant socio-demographic and work-related characteristics, an increased risk of moderate burnout was found for doctors surveyed in 2004 and 2007 (OR 1.6, 95% CI 1.3 to 2.0), general practitioners (OR 1.6, 95% CI 1.3 to 2.0) and French-speaking doctors (OR 1.