CrossRef 12. Service RF: American Chemical Society meeting. Nanomaterials show signs of toxicity. Sci 2003, 300:243.CrossRef 13. Bermudez E, Mangum JB, Wong BA, Asgharian B, Hext PM, Warheit DB, Everitt JI: Pulmonary Luminespib cell line responses of mice, rats, and hamsters to subchronic inhalation of ultrafine titanium dioxide particles. Toxicol Sci 2004, 77:347–357.CrossRef 14. Lin ZQ, Xi ZG, Chao FH: Effects of carbon nanotubes on rat aortic endothelium damage. J Environ Health 2008, 12:1126–1132. 15. Rai AJ, Zhang Z, Rosenzweig J, Shih I, Pham T, Fung ET, Sokoll LJ, Chan DW: Proteomic approaches to tumor
marker discovery. Arch Pathol Lab Med 2002, 126:1518–1526. 16. Schwarze PE, Øvrevik J, Låg M, Refsnes M, Nafstad P, Hetland RB, Dybing E: Particulate matter properties and health effects: consistency of epidemiological and toxicological studies. Human & Exper Toxico 2006, 25:559–579.CrossRef 17. Rao KM, Ma JY, Meighan T, Barger MW, Pack D, Vallyathan V: Time course of gene expression of inflammatory mediators in rat lung after diesel exhaust particle exposure. Environ Health Perspec 2005, 113:612–617.CrossRef 18. Liu H, Yang D, Yang H, Zhang H, Zhang W, Fang YJ, Lin Z, Tian L, Lin B, Yan J, Zhu-Ge X: Comparative study of respiratory tract immune selleck products toxicity induced by three sterilisation nanoparticles: silver, zinc oxide and titanium dioxide. J Hazard Mater 2013, 248–249:478–486.CrossRef
19. Lin ZQ, Xi ZG, Chao FH, Yang DF, Zhang HS, Lin BC, Zhang W, Liu HL, Sun X: ICAM-1 and VCAM-1 expression in rat aortic endothelial cells after single-walled carbon nanotube exposure. J Fosbretabulin Nanosci Nanotechnol 2010, 10:8562–8574.CrossRef 20. Lin ZQ, Liu LH, Xi ZG, Huang JH, Lin BC: Single-walled
carbon nanotubes promote rat vascular adventitial fibroblasts to transform into myofibroblasts by SM 22 -α expression. Int J Nanomedicine 2012, 7:4199–4206.CrossRef 21. Cheng WW, Lin ZQ, Ceng Q, Wei BF, Fan XJ, Zhang HS, Zhang W, Yang HL, Liu HL, Yan J, Tian L, Lin BC, Ding SM, Xi ZG: Single-wall carbon nanotubes induce oxidative stress in rat aortic endothelial cells. Toxicol Mech Methods 2012,22(4):268–276.CrossRef Staurosporine 22. Cheng WW, Lin ZQ, Wei BF, Zeng Q, Han B, Wei CX, Fan XJ, Hu CL, Liu LH, Huang JH, Yang X, Xi ZG: Single-walled carbon nanotube induction of rat aortic endothelial cell apoptosis: reactive oxygen species are involved in the mitochondrial pathway. Int J Biochem Cell Biol 2011, 43:564–572.CrossRef Competing interests The authors declare that they have no competing interests. Authors’ contributions ZQL and LM participated in the design of the study, carried out the experiments, and drafted the manuscript. BCL checked the manuscript grammar and modified the draft of the manuscript. HSZ performed the statistical analysis. ZGX designed the study and guided this work. All authors read and approved the final manuscript.