Dissatisfaction was defined as no change in symptoms, and/or de novo important symptoms.\n\nThe overall rate of good satisfaction was 74.7% (62/83), check details moderate satisfaction 15.6% (13/83), and only 9.6% (8/83) were not satisfied. There was no statistical difference among the six different groups (sacrocolpopexy only, plus TVT, plus TVT and hysterectomy, sacrocolpopexy and previous hysterectomy, sacrocolpopexy and TVT with previous hysterectomy), concerning the pre and post operative clinical signs and post operative symptoms. There was a statistically significant difference (p=0.038) regarding dissatisfaction and

prolapse relapse between the group that had a previous total hysterectomy combining sacrocolpopexy with TVT and all other groups. The most frequent post operative symptoms were stress incontinence, dysuria and constipation. No severe complications and mesh erosion were observed, despite the two cases of mesh detachment.\n\nConclusions: Laparoscopic double synthetic mesh sacrocolpopexy seems to be a safe and effective treatment of genito-urinary prolapse, with good overall long term outcomes and benefits of the minimal access approach. The presence of the remaining Epigenetics inhibitor cervix after subtotal hysterectomy, seems to enhance the results of laparoscopic sacrocolpopexy.. Further randomised studies are needed to confirm our results

and to compare this method to open and/or vaginal approach. Hippokratia 2009; 13 (2): 105-109″
“Genetic variability of modulus of elasticity (MOE) was investigated in three genetic trials, including two progeny (16 years old) and one clonal (19 years old) trials of hybrid larch (Larix

x eurolepis Henry). MOE was directly assessed on standing AZD1208 datasheet trees using the Rigidimeter, a bending device, and related to other traits including height, BH diameter and wood density. Mean MOE ranged from 5,183 to 9,228 MPa among families in the progeny trials and from 4,591 to 11,486 MPa in the clonal trial. Among traits studied, MOE was one of the most variable traits. It was strongly and positively related to wood density at both the individual and genotype mean levels. Interestingly too, wood stiffness did not seem, or only weakly, unfavourably linked to stem diameter at the phenotypical level, but it was negatively or not correlated to diameter at the genetic level. As well, MOE showed a high GxE stability over the two progeny trial sites. Narrow-sense heritabilities for MOE were moderate (around 0.36). In all three trials, they were lower than those for wood density or total height, and of the same level as for diameter. Improvement of wood stiffness of hybrid larch using the Rigidimeter seems possible and promising genetic gains are expected. Impacts of selection for growth traits on MOE are also discussed.”
“Micafungin concentrations in plasma and burn eschar after daily intravenous infusion (1 h) of micafungin (200 to 300 mg) were investigated for six patients with severe burns.