PubMed 4. Saslaw S, Eigelsbach HT, Wilson HE, Prior JA, Carhart S: Tularemia vaccine study. I. Intracutaneous challenge. Arch Intern Med 1961, 107:689–701.PubMed 5. Eigelsbach HT, Downs CM: Prophylactic effectiveness of live and killed tularemia vaccines. I. Production of vaccine and evaluation in the white mouse and guinea pig. J Immunol 1961, 87:415–425.PubMed 6. Larsson P, Oyston PC, Chain P, Chu MC, Duffield M, Fuxelius HH, Garcia E, Halltorp G, Johansson D, Isherwood KE, et al.: The complete genome sequence of Francisella tularensis find more , the causative agent of tularemia. Nat Genet 2005,37(2):153–159.PubMedCrossRef 7. Gallagher LA, Ramage E, Jacobs MA, Kaul R, Brittnacher M, Manoil C: A comprehensive transposon
mutant library of Francisella novicida , a bioweapon surrogate. Proc Natl Acad Sci USA 2007,104(3):1009–1014.PubMedCrossRef 8. Su J, Yang J, Zhao D, Kawula TH, Banas JA, Zhang JR: Genome-wide identification of Francisella tularensis virulence determinants. Infect Immun 2007,75(6):3089–3101.PubMedCrossRef 9. Anthony LD, Burke RD, Nano FE: Growth of Francisella spp. in rodent macrophages. Infect Immun 1991,59(9):3291–3296.PubMed 10. Clemens DL, Lee BY, Horwitz MA: Virulent and avirulent strains of Francisella tularensis prevent acidification and maturation of
their phagosomes and escape into the cytoplasm in human macrophages. Infect Immun 2004,72(6):3204–3217.PubMedCrossRef 11. Golovliov I, Baranov V, Krocova Z, Kovarova H, Sjostedt A: An attenuated strain of the facultative intracellular bacterium Francisella tularensis can escape the phagosome of monocytic cells. Infect Immun Regorafenib 2003,71(10):5940–5950.PubMedCrossRef 12. Santic M, Molmeret M, Klose KE, Jones S, Kwaik YA: The Francisella tularensis pathogenicity island protein IglC and its regulator MglA are essential for modulating phagosome biogenesis and subsequent bacterial escape into the cytoplasm. Cell Microbiol 2005,7(7):969–979.PubMedCrossRef 13. Qin A, Scott DW, Thompson JA, Mann BJ: Identification of an essential Francisella tularensis subsp.
tularensis virulence factor. Infect Immun 2009,77(1):152–161.PubMedCrossRef 14. Gil H, Platz GJ, Forestal CA, Monfett M, Bakshi CS, BI 10773 molecular weight Sellati TJ, Furie MB, Benach JL, Thanassi DG: Deletion of TolC orthologs L-NAME HCl in Francisella tularensis identifies roles in multidrug resistance and virulence. Proc Natl Acad Sci USA 2006,103(34):12897–12902.PubMedCrossRef 15. Bina XR, Lavine CL, Miller MA, Bina JE: The AcrAB RND efflux system from the live vaccine strain of Francisella tularensis is a multiple drug efflux system that is required for virulence in mice. FEMS Microbiol Lett 2008,279(2):226–233.PubMedCrossRef 16. Mohapatra NP, Soni S, Bell BL, Warren R, Ernst RK, Muszynski A, Carlson RW, Gunn JS: Identification of an orphan response regulator required for the virulence of Francisella spp. and transcription of pathogenicity island genes. Infect Immun 2007,75(7):3305–3314.PubMedCrossRef 17.